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What are the trade-offs
Tirzepatide is a dual GIP/GLP-1 receptor agonist, while Retatrutide (LY3437943) adds a third target the glucagon receptor making it a triple agonist studied for broader metabolic effects
In an angiotensin-induced cardiac remodeling model, it exerts anti-fibrotic effects through PPAR- activation [177]
Sci 23, 140 (2022)
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That determination could finalize the rule as proposed, modify it based on submitted comments, or withdraw the proposal
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