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The primary outcome was change in HbA1c from randomisation to the end of treatment, secondary outcomes included body weight change

GLP-1 medications have become one of the most talked-about tools for weight loss and diabetes managementbut there's much more to the story

With close to 5000 downloads, it is among the most trafficked tool in the MCT2D Resource Library.

What makes this moment notable is what it says about how we got here

Current evidence suggests minimal transfer into breast milk, but clinical guidance emphasizes individualized medical consultation before starting any GLP-1 medication

The standard FDA tirzepatide dosing schedule moves through six weekly dose levels: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg, with at least four weeks between steps