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GLP-1 helps regulate appetite and blood sugar by: Reducing hunger signals in the brain Slowing gastric emptying Increasing feelings of fullness after meals Originally developed for type 2 diabetes, semaglutide was later shown at higher doses to produce significant, sustained weight loss

This phenomenon, called tachyphylaxis or tolerance, doesn't mean the medication has failedit means your body has adapted, and your treatment strategy may need adjustment

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Consult your prescribing provider or compounding pharmacy for the beyond-use date specific to your prescription