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The timeline for these changes depends on each medication's specific half-life

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When you diet, your brain senses reduced energy intake and responds by: Increasing hunger hormones Slowing metabolism to conserve energy Intensifying cravings for high-calorie foods Making you feel tired, irritable, or obsessed with food These responses are designed to protect you from starvation

Compared to the other trials investigating GLP-1RAs, the ELIXA trial included T2D patients with recent acute coronary syndrome (ACS), suggesting that perhaps their CV risk was too severe to demonstrate a simple decline in CV events via short-term pharmacological intervention

This evaluation may include: Review of your complete medication list for other drugs that might affect sleep Assessment of diabetes control through HbA1c and glucose monitoring data Screening questionnaires for sleep apnoea, depression, or anxiety Physical examination to identify other potential causes Consideration of referral to a sleep specialist if appropriate Do not stop taking Ozempic without medical guidance