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What semaglutide matches well For people who were on lower tirzepatide doses (2.5 to 7.5 mg), semaglutide at appropriate doses can provide nearly equivalent appetite suppression and metabolic benefit

Meaningful weight loss (5%+ of body weight) typically appears by weeks 612 of consistent weekly dosing

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The levels of incretins including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic hormone rise in response to a meal, and they are rapidly degraded by the enzyme dipeptidyl peptidase 4 (DPP-4) [5]