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Glucagon-Like Peptide 1 Receptor Agonists and the Eye AT A GLANCE Glucagon-like peptide 1 receptor agonists (GLP-1RA) are FDA-approved for treating type 2 diabetes and are commonly used in weight loss regimens

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In terms of the anorectic pathways in the brain, the anorectic effects of MC4R agonism are mediated by downstream responses of POMC/CART neurons [26, 27]

10.3390/toxics13070594 14 EngstrmA.WintzellV.MelbyeM.SvanstrmH.EliassonB.GudbjrnsdottirS.et al (2024)

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The study was limited, involving only 45 participants, and used liraglutide rather than the more potent semaglutide or tirzepatide