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Description
With reduced appetite and calorie intake

Liver: In the ESSENCE Phase 3 trial, 62.9% of patients on semaglutide achieved resolution of steatohepatitis without worsening fibrosis, versus 34.1% on placebo

J Clin Endocrinol Metab 2015;100:2849-52.ArticlePubMedPMC 822

In late 2024, the FDA lifted the shortage designation for tirzepatide and directed compounders to cease production
In Los Angeles County, use is still not widespread as doctors have to secure prior authorizations through Medicaid managed-care organizations and teach patients how to inject themselves at home

The most common ones include: Nausea Vomiting Diarrhea or constipation Stomach pain Fatigue Most side effects are mild and improve over time
