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Avoid single-nutrient megadoses unless directed by a clinician

Up to 40 percent of patients experience nausea in the early weeks of treatment, particularly during dose escalation

Using pharmacological agents with cardiovascular and renal benefits, including reninangiotensin system inhibitors and sodium-glucose cotransporter-2 inhibitors, is paramount

Structurally identical to native exendin-4, exenatide is a chemically synthesized peptide with clinical applications in the management of type 2 diabetes

Adverse effects were similar to dulaglutide, and above all, regarding gastrointestinal adverse events, that was dose-related (231% for 1 mg LY3298176, 327% for 5 mg LY3298176, 510% for 10 mg LY3298176, and 660% for 15 mg LY3298176, 426% for dulaglutide, 98% for placebo [19]