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Glucose-lowering drugs have exhibited neuroprotective effects against cognitive decline, but conflicting results of two studies published in JAMA Neurology suggest the need for additional research

Response timelines vary based on biomarkers, GI tolerance, and individual metabolic factors

Subsequently, it was shown that weight loss caused an immediate decrease of pancreas fat only in people with type 2 diabetes and also that postprandial incretin spikes after bariatric surgery had no role in normalising fasting plasma glucose

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