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The GIP receptor pathway works alongside GLP-1 to amplify appetite suppression, enhance insulin sensitivity, and increase energy expenditure

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elegans strains, growth conditions, and maintenance The strains Bristol N2 (WT), DH26 [ fer-15(b26) II ], DA2123 [ lgg-1p:GFP:lgg-1+rol-6(su1006) ], MAH215 ( sqIs11 [ lgg-1p:mCherry:GFP:lgg-1 + rol-6 ]), DA1116 [ eat-2(ad1116) II ], CB4037 [ glp-1(e2141) III ], and CB1370 [ daf-2(e1370) III ] were obtained from the Caenorhabditis Genetics Center (University of Minnesota, Minneapolis, Minnesota, USA)

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