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GLP-1 receptor activation affects vascular function, and changes in microvascular blood flow could alter how sensory nerves in the skin behave
New England Journal of Medicine (2025) This groundbreaking trial evaluated tirzepatide in 731 patients with heart failure with preserved ejection fraction (HFpEF) and obesity
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Lifestyle interventions, such as dietary modification and increased physical activity, are foundational but often insufficient for achieving substantial and sustained weight loss
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