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To reduce the development of adverse CVEs among patients with NAFLD and type 2 diabetes, it is also essential to have routine cardiovascular risk assessments and timely implementation of GLP-1RAs and SGLT2 inhibitors

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Finally, amelioration of the G/F-actin ratio restores the disruption of the YAP signal induced by high glucose and upregulates the transcription factors Neurod1, Foxa1, and Foxa2, which are responsible for controlling L-cell differentiation [30] (Fig