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10.1172/jci.insight.159863 73 KojimaM.TakahashiH.KuwashiroT.TanakaK.MoriH.OzakiI.et al (2020)

It is particularly effective for individuals with a BMI of 30 or higher, or those with a BMI of 27 or higher who also have weight-related health issues

Topical pain relief creams, physical therapy, heat or ice therapy, and short-term muscle relaxants offer drug-free or lower-risk alternatives

Formal rulemaking would take considerably longer even in the best case

Larger studies must be conducted and for a longer period because the number of patients included in these studies was relatively small and they were followed up for a brief period of time (in most cases 612 months)

And a growing amount of them have thought about including them in their health plans