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doi: 10.1016/j.molmet.2022.101590

In the absence of cAMP, the regulatory region of Epac2 is responsible for the autoinhibition of the catalytic function

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Diabetic Retinopathy Complications : There is evidence suggesting that rapid improvements in blood sugar levels due to drugs like Ozempic may exacerbate diabetic retinopathy in patients with pre-existing diabetes