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Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line

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This rerouting of the digestive system leads to several effects that contribute to weight loss

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Once released, it does several things at once: it prompts your pancreas to release insulin proportional to your current glucose level, signals your brain that you're full, slows the rate at which food leaves your stomach, and suppresses glucagon - the hormone that would otherwise push glucose higher between meals