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Major determinants of MASH pathogenesis, including gut microbiota, skeletal muscle, and visceral adipose tissue, are potential targets of innovative drugs in this field

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So understanding the biology alone didnt get us there, but it was absolutely necessary before we could move on to the next phase. Each new leap in understanding may not be prize-worthy in isolation, but with each one, the door cracked open wider, expanding the number of people who could benefit from GLP-1 and other gut-hormone-based treatments

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10.1530/EC-19-0268 [DOI] [PMC free article] [PubMed] [Google Scholar] 62.AlTowayan A, Alharbi S, Aldehami M, Albahli R, Alnafessah S, Alharbi AM