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9 (2025): e70240

As a crucial part of producing energy, NAD is significantly involved in DNA repair and cell repair

It comes down to how the drugs are designed: while semaglutide acts only on GLP-1 receptors, tirzepatide is a dual-target drug that also acts on GIP receptors (GIP, or gastric inhibitory polypeptide, is another hormone like GLP-1 that helps regulate insulin and blood sugar)

doi:10.1001/jamaophthalmol.2025.0349 MSc

When you eat, GLP-1 is naturally released from your gut these medications mimic that hormone at sustained, higher concentrations

Dose-related increases in heart rate have been observed, peaking around 24 weeks before declining