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However, the MHRA has not analyzed their safety when used outside approved indications like weight loss in individuals who are not overweight or obese

In clinical trials, psychiatric adverse events occurred at similar rates in treatment and placebo groups, suggesting the medication itself doesnt commonly cause negative mental health effects

doi: 10.1001/jama.2024.5003
Instead, effective weight management depends on matching the formulation, dosing strategy, and appetite-regulating strength to an individuals goals, tolerance, and lifestyle
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