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A Phase 2 trial published in The New England Journal of Medicine in 2023 enrolled 338 adults with obesity

Results from TRIUMPH-1 and TRIUMPH-2 (general obesity, no OA requirement) are expected mid-to-late 2026

Each differs in effectiveness, safety, and recovery time

Comparison: Air Bubble Scenarios and Risk Assessment Key Takeaways Air bubbles under 0.5mL in a retatrutide syringe pose zero embolism risk when injected subcutaneously

In animal and cell models, GLP-1 has been shown to impact the development and/or progression of atherosclerotic plaques
