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Reports of semaglutide-associated hepatotoxicity are exceedingly rare

Researchers from Monell Chemical Senses Center have identified a specific population of neurons in the brain that could be key to appetite suppression without nausea, a common side effect of GLP-1 drugs like Ozempic and Wegovy.

Electronic databases including PubMed, Embase, and Web of Science were searched from inception until August 2025 using keywords such as GLP-1 receptor agonist, diabetic retinopathy, glaucoma, age-related macular degeneration, ocular disease, and neuroprotection. The search focused on identifying preclinical studies, large-scale retrospective cohort studies, and post-hoc analyses of major clinical trials that evaluated the utility and potential mechanisms of GLP-1RAs in ophthalmic diseases

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Learn What to Expect During the First Week After Your Ozempic Shot With Care From Dr

Fatty liver: Can lead to fatty liver disease, which may progress to liver dysfunction, cirrhosis, or require liver transplant