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Watch For Diarrhea And Vomiting: Prevent Dehydration Early Gastrointestinal side effects can cause rapid fluid loss
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It enhances the secretion of insulin (which lowers blood glucose levels) in response to food intake, suppresses the secretion of glucagon (which raises blood glucose levels), slows gastric emptying to help control appetite and food intake, and promotes the health and survival of pancreatic beta cells
These additions do not change the dosing chart for the base medication
Topiramate calms overactive nerve signaling through several mechanisms: it enhances GABA-A inhibition, blocks voltage-gated sodium channels, dampens AMPA-type glutamate transmission, and mildly inhibits carbonic anhydrase
