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Plasma is approximately 90% water
A year later Bloom's group published a study which demonstrated that rats completely lost interest in food when GLP- 1 (7-36) was injected directly into the hypothalamus part of their brains
The GLP-1 drugs seemed to work across the board
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Patients who switched from a GLP-1 receptor agonist to the comparator drug, or vice versa, did not re-enter the cohort after switching
PMID: 18541709
