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Key genetic variants including GLP1R rs6923761, GIPR rs1800437, and MC4R rs17782313 influence how your body processes appetite-suppressing compounds

Am J Physiol-Endocrinol Metab 311:E471E479

Side Effects: Both have similar gastrointestinal side effects (nausea, vomiting, diarrhea)

Without adequate protein intake, the body pulls from muscle and connective tissue, including collagen, to meet its nutritional needs

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Under 150 pounds (under 68 kg) If you weigh under 150 pounds, you are on the lighter end of the clinical trial population, and lower doses may produce proportionally stronger effects