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Data availability The EHR database used in this study were obtained from TriNetX ( Abbreviations GLP-1RAs: Glucagon-like peptide-1 receptor agonists T2DM: Type 2 diabetes mellitus EHRs: Electronic health records SGLT2: Sodium-glucose cotransporter-2 DPP-4: Dipeptidyl peptidase-4 HR: Hazard ratios CI: Confidence intervals References Alfaris N, Waldrop S, Johnson V, Boaventura B, Kendrick K, Stanford FC (2024) GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review

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Quenching of the fluorescence signal of the coumarin-labeled IR protein was analyzed with the equation: Allosteric binding of ITP and IR Competitive binding assay 57 Primary BMECs were pre-seeded in 12-well plates (2 10 5 per well) and cultured at 37 C for 24 h

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