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Description
By week 8 to 10 at a stable dose, most patients are asymptomatic

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The proportion of participants achieving MWPC ( 5.76) in the SF-36v2 physical functioning score from baseline to week 72 was numerically higher with tirzepatide 10 mg (34.2%) and 15 mg (35.6%) than with placebo (24.1%

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Appetite suppression intensifies

If appetite has returned, this confirms receptor adaptation rather than behavioral drift
