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For more stubborn constipation, osmotic laxatives like polyethylene glycol (Miralax) are generally safe for regular use

Unlike some medications that lose effectiveness over time, incretin-based therapies maintain efficacy in multi-year studies

Both medications were titrated to their maximum approved doses

By improving blood sugar control and supporting reduced calorie intake, these therapies may support safe, steady, and sustainable weight loss when combined with a comprehensive care plan

Ozempic is in the class of drugs glucagon-like peptide-1 receptor agonists, but it selectively agonizes GLP-1 receptors