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Mounjaro is administered as a once-weekly subcutaneous injection, with doses typically starting at 2.5 mg and potentially increasing to a maximum of 15 mg depending on individual response and tolerability

Eli Lilly and Company (2025)

Despite this reassuring human data, UK product information contains warnings and precautions regarding thyroid C-cell tumours based on rodent data

In the simple, preliminary model with only linear effect of time on GLP-1 RA and duration of HH, exposure to GLP-1 RA for 1 year was associated with around 30% (95% CI 20% to 40%) lower estimated ferritin levels

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Retatrutide has been investigated in the literature as a simultaneous agonist of the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon (GCGR) receptors