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To minimize weight rebound during and after the transition phase, focus on maintaining the dietary patterns you established while on semaglutide: prioritizing protein intake, spacing meals appropriately, and staying hydrated

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Regulator: MHRA (UK medicines)

This change creates an opportunity to reset your eating patterns, but success depends on choosing foods that satisfy nutritional needs while respecting your body's new signals

The overall discontinuation rates due to adverse events are similar, suggesting that the dual mechanism doesnt necessarily increase tolerability issues

Consistent with this effect, dulaglutide reduced atherosclerotic lesion size in Apoe / mice with streptozotocin-induced diabetes (5)