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Cone opsin, is clearly delocalized around the inner segments and cell bodies in regions where the RPE is bricked and builds up large deposits underneath those RPE cells filled with taurine and glutamate and ringed by cone opsins suggestive of RPE defects in both retinoid processing (Baehr et al., 3, 6)

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10.1038/s41380-020-0704-x 43

4D, E, Supplementary Fig

EVs have the ability to transport miRNAs, which can either influence the physiological processes of recipient cells or exacerbate their pathological state, depending on the status of the donor cell (Petralla et al., 2021)