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ROS Lysosomes are particularly prone to ROS-mediated damage due to their iron content, which facilitates the production of highly reactive hydroxyl radicals through Fenton-type reactions (H 2 O 2 +Fe 2+ Fe 3+ +HO + OH ) 19 (Figure 2)

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It is still used with elderly diabetic individuals in these countries, though the WHO model list of essential medicines (2015) reported that it is not suitable for those aged above 60 years 28
5 mg: 3 vials: 9 mL 1 10 mL bottle 10 mg: 2 vials: 6 mL 1 10 mL bottle Alcohol Swabs: One for the vial stopper + one for the injection site each day

doi: 10.1182/blood-2006-09-047712

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