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Epub 2018 Feb 23

Common side effects The most frequently reported side effects are mild and transient: Dizziness (most common, usually related to injection speed) Headache (typically resolves within 24 hours) Skin flushing (related to vasodilation effects) Nausea (more common at higher doses) Fatigue or insomnia (varies by individual) Agitation or anxiety (infrequent) Weight loss (reported in some longer-term studies) Feeling hot (transient, related to administration) Most of these side effects correlate with administration speed rather than the compound itself

In another study, silymarin decreased amiodarone levels and amiodarone-induced lysosomal phospholipidosis in the liver (4)

doi: 10.1191/1352458502ms860oa 58 FilippiM.RoccaM

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