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GSH is a tripeptide (glutamic acid, cysteine and glycine)

In vivo studies confirmed that Ghrelin significantly activated the BMP6/SMAD1 signaling pathway in the brain tissue of AD mice, thereby inhibiting microglial ferroptosis, promoting microglial polarization toward the M2 phenotype, and ameliorating learning and memory deficits in AD mice (Guo et al., 2025b)

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The p62 abundance further increased upon treatment with an inhibitor of autophagosome-lysosome fusion Bafilomycin A1 (BafA1), confirming normal autophagic flux in the polysomic cells, as previously reported 8,19 (Fig
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