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Mitochondrial dysfunction, a key feature of AD, further exacerbates ROS production, impairs ATP generation, disrupts calcium homeostasis, and ultimately induces neuronal apoptosis (Bhatt et al., 2021)

Low concentrations of estrogens promote Th1 proinflammatory responses, whereas higher levels induce Th2 humoral immunity

2,3 Correction of deficiency different routes of administration Depending on the cause of the deficiency, different strategies to correct it can be applied, although in conventional medical practice the most common treatment is intramuscular (i.m.) injection of B12

Jia M, Ren W, Liu Y, Wang C, Zheng X, Zhang D, et al

The in vivo spin trapping and electron paramagnetic resonance (EPR) spectroscopy revealed that cysteine deficiency significantly increased lipid-derived radicals in BAT with undetectable signals in white adipose tissue (WAT) (Fig

Methods Enzymol 77:5059 Prabakaran D, Ashokkumar N (2013) Protective effect of esculetin on hyperglycemia-mediated oxidative damage in the hepatic and renal tissues of experimental diabetic rats
