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However, in Sh-Chac2 cells, these IFN-Iinduced effects were markedly ablateddemonstrating that Chac2 is a key mediator linking IFN-I signaling to GSH metabolic reprogramming and N1-type polarization

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Cell Cycle Progression of Glutathione-Depleted Human Peripheral Blood Mononuclear Cells Is Inhibited at S Phase

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Combination therapies may not only enhance therapeutic outcomes but also provide more treatment options to meet individual patient needs