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These effects drive inflammatory processes and nitro-oxidative pathways [100] and the resultant excess of reactive oxygen species may induce oxidative damage, aggravating systemic tissue damage and contributing to more severe COVID-19 [101]

[DOI] [PubMed] [Google Scholar] 122.Mandracchia D., Denora N., Franco M., Pitarresi G., Giammona G., Trapani G
109,110 Other research shows ginkgo flavonoids can directly inhibit thrombin activity

The main derivatives of astragalus are methylxanthine, theophylline (1,3-dimethylxanthine), theobromine (3,7-dimethylxanthine), and caffeine (1,3,7-trimethylxanthine) (Li et al., 2017)

Homocysteine can also be high with folate deficiency so folate should also be measured to rule that out

Whilst AOD-9604 was not successful in human trials aimed at obesity, the Company believes there is sufficient efficacy data to enable a potential food, drink or dietary supplement product to be successfully marketed in the US.'' ASADA investigators are expected to hand down their report in the next fortnight.
