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PMID: 41803228 J Biotechnol 2025 Nov 12:410:1-9

Since a succinyl-group transfer introduces a relatively large structural moiety (100 kDa) compared to lysine methylation and acetylation [16], it has been proposed that succinylation modification could induce a relatively large shift in the charge and the structural alteration with significant effects on the function of the target protein

[DOI] [PMC free article] [PubMed] [Google Scholar] Luo J, Xu T, Wang X, Ba X, Feng X, Deepak V, Zeng X

Bailon-Moscoso et al., 2017

Mol Breed 7:301315 Mittler R (2002) Oxidative stress, antioxidants and stress tolerance

Since glutathione is a natural component of human cells, the adverse effects seen with oral capsules are expected to be mild, similar to those with high-dose vitamin supplements