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Pharmaceutical agents such as Cox-2 inhibitors, thalidomide, megestrol, medroxyprogesterone acetate, melatonin, and DCA, and supplemental nutrients or antioxidants from food [35], such as -3 poly-unsaturated fatty acids, vitamin C, vitamin D, vitamin E, -hydroxy--methylbutyrate (HMB) [36] and lycopene, represent potential anti-cachexia treatments that are being explored in clinical trials

[PubMed] [Google Scholar] 8.Chen Z.-Y., Zhang Y

This water-soluble vitamin, chemically known as L-ascorbic acid, is a critical cofactor in different enzymatic reactions, particularly in collagen synthesis, carnitine biosynthesis, and neurotransmitter production