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Cardiovascular Benefits Evidence suggests direct cardiac benefits independent of anti-obesity properties

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The insect gene myo , which is a homolog of GDF11 and MSTN , is strongly expressed in muscle and glial cells and has been shown to promote neuronal development and remodeling 13,40,41 , prevent age-related muscular dysfunction 16 , and extend the lifespan in Drosophila 16,42

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Results from a 2017 study show an association with consuming high-dose B6 and B12 vitamin supplements over 10 years with an increase in lung cancer risk in men, especially smokers (Brasky, 2017)
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