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Conclusions : HSCT with PTCy for sAML in CR1, from yHaplo vs oMSD, resulted in similar transplantation outcomes, besides a higher incidence of NRM and slower neutrophil engraftment, while a lower incidence of ext cGvHD in the yHaplo compared to the oMSD

Current approaches include: Continuous Use Approach: Based on clinical trials that used continuous daily administration for 12-24 weeks without scheduled breaks

Clinical application Safety A serious issue in developing these therapeutics is in vivo safety

Salvia Fruticosa induces vasorelaxation in rat isolated thoracic aorta: role of the PI3K/Akt/eNOS/NO/cGMP signaling pathway

Not for injection

Severe vitamin B12 deficiency in an exclusively breastfed 5-month-old Italian infant born to a mother receiving multivitamin supplementation during pregnancy. BMC pediatrics 12.1 (2012): 1-5