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By starting signal transduction pathways, increased ROS generation during inflammation may cause recurrent DNA damage and apoptosis and activate proto-oncogenes

Smoking, lifestyle, and viral infections also play a role in gene-environment interactions in RA disease

International Journal of Molecular Sciences, 20(21), 5407

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Lushchak V.I

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): A double-blind, randomised, phase 3 trial

SLICE/LIFE = Streamlined Longitudinal Interview Clinical Evaluation from the Longitudinal Interval Follow-up Evaluation