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Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is the gold standard for quantifying dihexa in plasma, with a lower limit of quantification typically around 15 ng/mL depending on sample preparation and ionization efficiency

For example, consider acetic acid in a solution with water at a bulk pH equal to the p K a (i.e., 4.8)

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Add it slowly down the vial wall and let it dissolve without shaking

There are also people who combine it with micro needling