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In some embodiments, the MDT for an active agent from a formulation or device described herein is from about 30 hours to about 1 week
2017;28(suppl_5):v26994
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doi: 10.1016/j.bcp.2015.02.003 214 LeeE
CSCs are a subpopulation of tumor cells with the capability to self-renew and differentiate, which drives tumor progression and metastasis
GHD is associated with increased visceral fat and dyslipidemia, while GH excess in acromegaly induces IR and glucose intolerance, adding cardiometabolic burden to the direct myocardial effects of GH/IGF-1 excess
