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First, we performed a sensitivity analysis of l-carnitine or acetyl-l-carnitine supplementation on serum AST and ALT levels after excluding a study of patients with decompensated cirrhosis [31] (Figure S4)

Produto esgotado

After transporting fatty acids from the cytoplasm to the mitochondria, L-carnitine returns to the cytoplasm for the next cycle using carnitine-acylcarnitine translocase (CACT), while acetyl-CoA may enter (under aerobic conditions at low concentrations of ATP) -oxidation, with the final production of acetyl-CoA (Figure 2) [83]

Supplementary Information The online version contains supplementary material available at 10.1186/s12916-022-02477-z

Ganjam, GK

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