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Patients with chronic pancreatitis have lower levels of glutathione, cysteine, and glycine.[ref] Increasing cysteine levels with NAC is protective against pancreatic damage.[ref] Schizophrenia: Several research studies show that people with schizophrenia have lower glutathione levels in certain regions of the brain.[ref] In aging: The studies on glutathione in aging show that there is usually a general decrease in serum glutathione levels as we age

This Schiff base intermediate is crucial because it establishes the alpha carbon atom in glutamates stereochemistry

Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis

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To examine the interaction between glutathione levels and ROS, infected A6 cells were first stained with 50 M mBCI in 70% L15 media for 1 hour, then stained with 10 M DCFH-DA for 30 mins