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Subsequently, the ascorbate levels decreased, whereas dehydroascorbate levels significantly increased

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[DOI] [PubMed] [Google Scholar] 455.Pastore, A
While a typical oral supplement might deliver 200-1,000mg of vitamin C with limited absorption, high-dose IV therapy can safely administer 10,000-50,000mg (10-50 grams) in a single session

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Several lines of evidence have suggested that oxidative DNA damage is increased in relation to aging