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This variability highlights the importance of personalized treatment planning

Users maintaining detailed logs can correlate outcomes with storage conditions, identifying problems early

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For example, a proportion of patients with Parkinson's disease develop dementia, Cognitive impairment also occurs in the Parkinson-plus syndromes of progressive supranuclear palsy and corticobasal degeneration (and the same underlying pathology may cause the clinical syndromes of frontotemporal lobar degeneration)