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Supplementary permutation-based analysis at the descriptor-family level was consistent with these observations (Supplementary Tables S5, S6)

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This review aims to provide a clearer understanding of the role of Nrf2 in the regulation of oxidative stress and inflammation, highlighting its importance in the prevention and treatment of a wide range of diseases, including cancer, neurodegenerative disorders, cardiovascular and pulmonary diseases, diabetes, inflammatory conditions, ageing and infections such as COVID-19