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Antioxidant Protection The most commonly known function of glutathione is related to its role as an antioxidant

53,55,56,58,59,61,64 Impact of Intestinal Microbiota The fact that gut inflammation might result in leaky gut and translocation of bacteria to the portal system and the liver has raised the possibility that bacteria potentially contribute to PSC

Dhiman RK, Sharma A, Roy A, Premkumar M, Taneja S, Kumar A et al (2020) Role of fecal microbiota transplantation in severe alcoholic hepatitis: assessment of impact on prognosis and short-term outcomes

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Antioxidants Why theyre used: Antioxidants protect cells against damage from free radicals, which increase inflammation and are believed to contribute to the development of disease

Using double mutants of hTrxR1 C497S,U498C and hTrx1 C35S,C73S , we trapped the intermediate state of the oxidative half-reaction