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It protects the cancerous cells by conferring resistance to chemotherapeutic drugs

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[DOI] [PubMed] [Google Scholar] 55.Moreira L., Arajo I., Costa T., Correia-Branco A., Faria A., Martel F., Keating E

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This step might involve acid-base catalysis by the active-site cysteinyl thiolate (which could explain an effect of the second cysteinyl residue), and/or the conserved lysine residue, yielding GS in analogy to glutathione transferases (Fig

The addition of lipoic acid further increased improvements in both clinical symptoms and NCV