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Mol Cell Neurosci 73:1331 [DOI] [PMC free article] [PubMed] [Google Scholar] 46.Robbins JP, Price J (2017) Human induced pluripotent stem cells as a research tool in Alzheimers disease

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TLR2 triggers the activation of nuclear factor kappa-B (NF-B) via IL-1R-associated kinase 4 (IRAK4), IL-1R-associated kinase 1 (IRAK1), and tumor necrosis factor receptor-associated factor 6 (TRAF6), ultimately leading to the expression of inflammatory mediators and chemokines, namely chemokines chemokine (C-X-C motif) ligand(CXCL) 8 and CCL20 [105]